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Always follow the specific titration guidance in the product's SmPC

Key variants in the GLP-1 receptor gene (GLP1R rs6923761), GIPR pathway, FTO gene (rs9939609linked to appetite regulation), and MC4R (rs17782313central satiety signaling) influence how individual bodies respond to GLP-1 agonists

PlexusDx offers the Precision Peptide Genetic Test, an add-on test available after your first month of treatment that maps 14 pathways and 49 peptides to reveal your individual GLP-1 and GLP-Squared response potential

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A Cox proportional hazards model was used to test for non-inferiority against the pre-specified risk margin of 1.3 for the hazard ratio (HR) of the composite of CV death, myocardial infarction (MI), or ischemic stroke (MACE) and if non-inferiority was demonstrated, to test for superiority on the two primary endpoints: 1) the composite of hospitalization for heart failure or CV death, and 2) MACE

This includes ensuring optimal levels of specific nutrients like potassium, magnesium, zinc, chromium, polyphenols and fibers, as well as specific strains of probiotics