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The most common side effects of Jardiance and Januvia include: Jardiance: Urinary tract infection (UTI) Genital infections Upper respiratory tract infections (URI) Increased urination Dyslipidemia Joint pain Nausea Januvia: Upper respiratory tract infection (URI) Runny nose and congestion Headache Januvia and Jardiance drug interactions and warnings Januvia and Jardiance each have interactions that must be considered before being prescribed

[3] Oral vs Injectable: Side Effect Comparison GI side effects: Similar frequency and severity Injection-site reactions: None with oral (advantage) Timing: Most side effects occur during dose escalation and improve with continued use When to Contact Your Doctor (Serious Warnings) Seek medical attention if you experience: Severe abdominal pain that won't go away (possible pancreatitis) Lump or swelling in neck, hoarseness, trouble swallowing (thyroid tumor warning) Signs of allergic reaction (rash, itching, swelling, difficulty breathing) Severe nausea/vomiting preventing you from keeping down fluids Vision changes (diabetic retinopathy risk) Is the Pill Right for You

Drug Interaction Studies In Vitro Assessment of Drug Interactions Sitagliptin is not an inhibitor of CYP isozymes CYP3A4, 2C8, 2C9, 2D6, 1A2, 2C19 or 2B6, and is not an inducer of CYP3A4

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