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This suggests that the antibody may exert a positive influence on energy metabolism and weight regulation by affecting the GIP signaling pathway, potentially achieved by reducing food intake, inhibiting fat storage, or increasing energy expenditure, etc

Tirzepatide patients in the trial also had fewer GI-related discontinuations (2.7% versus 5.6%)

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The most common reason is availability, as branded medications like Wegovy are frequently on the FDA shortage list, making them difficult to find at local pharmacies

However, some health insurance companies are starting to expand their coverage for GLP-1s