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Preclinical work on optimized tri-agonists demonstrates "best-of-both-worlds" profiles, achieving greater energy expenditure and deeper weight normalization than GLP-1-only comparators [4]

In this trial, mean weight loss was comparable to that of individuals with obesity treated with semaglutide

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While genetic testing for variants linked to non response is not common, it represents the next step in helping ensure patients are given therapies that work better for them

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This chronic overindulgence has contributed to rising rates of obesity, type 2 diabetes (T2D), substance abuse, mental health disorders and premature mortality