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A GLP-1 RA or tirzepatide may be considered as an add-on (to metformin plus an SGLT2 inhibitor) for glycaemic control, if initial therapy is insufficient

Most insurance companies want to see proof that you've tried to lose weight before theyll approve coverage for GLP-1 drugs

Counsel patients that GI side effects (nausea, vomiting) during GLP-1 RA titration could impair oral contraceptive absorption through vomiting-related missed doses, and recommend a backup method during the first 4 weeks of titration if vomiting occurs

Oral Medication Review : Weight-loss injections may reduce the effectiveness of oral HRT medications, particularly oral progestogens

For those who discontinue GLP-1s, implementing comprehensive lifestyle changes becomes crucial