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Metformin is a widely prescribed, first-line oral antidiabetic agent that acts primarily through activation of AMP-activated protein kinase (AMPK), a key regulator of glucose metabolism, insulin sensitivity, and inflammation 13,14
[1, 2] All that said, GLP-1 drugs work by mimicking the GLP-1 hormone in your body

o Additional glycemic control is needed, increase the dosage to 9 mg orally once daily

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