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Consequently, there is increased production of cytokines derived from T cells, such as TNF-, IFN-, IL-2, IL-17, and granulocyte-macrophage colony-stimulating factor, in the synovial fluid, leading to joint inflammation[40]
Tirzepatide is a dual agonist (GIP + GLP-1)
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3.3 Bone metabolism Addressing the acute changes in the postprandial state, GIP(3-30)NH 2 infusions diminished GIP-induced suppression of the bone resorption marker carboxy-terminal type 1 collagen crosslinks (CTX) in both healthy individuals (78)
