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Researchers will evaluate participants through clinical assessments examining classic measures of asthma symptom burden, lung function, and airway inflammation and metabolic and inflammatory markers, insulin, hemoglobin A1c, lipid profiles, and overall frequency of asthma-related events

doi: 10.1038/sj.ijo.0803695

Martins C et al

Weir had developed a perfused rat pancreas model that made it possible to measure the impact of GLP-1 (7-37) on insulin secretion by the minute

While this study was only performed in relatively lean female mice, which are mostly protected against diet-induced obesity, it is in line with a study performed in patients receiving tirzepatide, dulaglutide, or placebo, which showed that tirzepatide treatment dose-dependently decreased levels of ApoC-III and ApoB and the number of large triglyceride-rich lipoprotein particles and small LDL particles, suggesting a net improvement in atherogenic lipoprotein profile (Wilson et al