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The use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) has revolutionized the treatment of Type 2 Diabetes Mellitus (T2DM)

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Short-acting GLP-1 RAs, exenatide and lixisenatide, are associated with a transient (112 h) mean placebo- and baseline-adjusted 24-h HR increase of 13 beats per minute (bpm)

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