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medRxiv , 2025.03.06.25323524 (2025)

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Vital signs Blood pressure and heart rate were stable during the trial, mean arterial pressure was lower at 12 weeks in the exenatide group compared to placebo, 6.7 mmHg (3.6), P = 0.088, but there was no significant change within arms between baseline and 12 weeks (Supplementary Table 4)

Carvedilol activates nuclear factor E2-related factor 2/antioxidant response element pathway to inhibit oxidative stress and apoptosis of retinal pigment epithelial cells induced by high glucose

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GLP1R:Gnas fl/fl [sema] p = 0.0016, WT:Gnas fl/fl [sema] vs