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Timeline: When You'll Notice Weight Loss Changes Most patients begin noticing appetite suppression within the first 12 weeks of starting GLP-1 therapy, though visible weight loss typically appears around weeks 36

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These include reticuloendothelial system (RES) accumulation, immune modulation, or oxidative stress resulting from high surface reactivity or protein corona formation [554]

Survival rates after myocardial infarction also improved after GLP-1 administration

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