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These medications undergo rigorous clinical trials demonstrating efficacy and safety before receiving MHRA approval

Currently, a number of studies are employing multiparametric kidney MRI to assess the effects of semaglutide (NCT04865770) (52), tirzepatide (NCT05536804) (53), and retatrutide (NCT05936151) (54) on kidney fat accumulation and link these effects to changes in GFR and albuminuria

doi:10.2337/diabetes.54.8.2375 39

Diet and lifestyle modification are necessary but not sufficient for sustained body-weight loss in the majority of individuals with obesity [84]

16 Prioritize your peace: If someone repeatedly crosses boundaries or makes disrespectful comments, it's okay to temporarily step away from the conversation or distance yourself