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A pharmacogenomic profile can also clarify whether your GLP-1 response is biologically suboptimal versus a dosing or adherence issue

This is especially important for women and anyone over 40, populations where muscle preservation during weight loss is critical for long-term metabolic health

Hernandez N, Ige K, Mietlicki-Baase E, Molina-Castro G, Turner C, Hayes M, et al

As sitagliptin clearly reduced DPP-4 activity and increased GLP-1 levels in mice after BMT, these findings are consistent with impairment of GLP-1 action by bone marrowderived cells

Conversely, rapid appetite suppression can lead to undereating, which may affect energy levels or medication absorption for some antidepressants

89:1140-1145 [PubMed: 15001599] 117