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Most patients choose a day that positions the peak side effect window away from important professional or social commitments

Twice a day exenatide (5 vs 10 g twice daily for 5 days) was shown to slow gastric emptying by scintigraphy in T2D in a dose-dependent manner, associated with a reduction in postmeal plasma glucose and peak insulin concentrations (23)

This is the unique feature of tirzepatide different from GLP-1 only therapies

The dose may increase by 2.5 mg after at least four weeks on the current dose

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Troubleshooting If you cannot remove the Pen cap, gently twist the Pen cap back and forth, and then pull the Pen cap straight off