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Stopping the semaglutide 3 to 7 days prior to surgery was an independent risk factor for conversion to intubation, while the 14-day and 30-day cohorts had no independent risk factor for this complication

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However, as only male rats were tested in the aforementioned study, and since PPG neuron activation was recently shown to have divergent effects on food-motivated behavior and palatable food intake in male vs female rats (51), it is also likely that this PPG neuron accommodation disinhibits female behavior more, contributing to the higher prevalence of binge-like behavior in females, a speculation that needs to be tested

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