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They activate GLP-1 receptors in the pancreas, the gut, and critically, the brain
How it's been studied: Cell-culture and animal-model research has examined Retatrutide's combined activity at three receptors that together govern insulin release, food-intake signaling, and energy expenditure
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10.3892/ijmm.15.1.3 83
Journal of biological chemistry, 288(35), 25088-25097
