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Key safety signals observed in the Phase 2 trial included gastrointestinal adverse effects (nausea, vomiting, diarrhoea, and constipation), increases in resting heart rate, and gallbladder-related events consistent with the broader class of incretin-based therapies

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Among participants taking orforglipron, adherence to the treatment regimen was monitored to assess efficacy and safety outcomes

Mounjaro also differentiates itself by targeting people with severe obesity, said Vishal Manchanda, analyst at Systematix Institutional Equities

Return to refrigerator promptly, and if the solution will not be used within the stability window, prepare fresh reconstituted material