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Evidence suggests that GLP-1 receptor agonists can effectively reduce visceral adipose tissue, though the degree to which this reduction is preferential compared to subcutaneous fat continues to be investigated

Sustainable weight management often involves making healthy changes to daily habits and routines

The weight loss from GLP-1 agonism derives from appetite suppression and possibly enhanced satiety signals

And GLP-1 is one of the metabolic signals researchers are now investigating

As noted, endogenous GLP-1 has a very short half-life of 12 min because it is rapidly degraded by the enzyme DPP-4, which results in low systemic levels