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doi: 10.1371/journal.pone.0198024
Tapering off GLP-1 medication is often suggested as a way to make that transition phase feel more manageable

These antioxidants support gut health and may help GLP-1 stay active longer by reshaping the gut microbiota (10)

Changes in circulation or shifts in body composition during significant weight reduction could potentially contribute to cramping, although this remains an area requiring further research

Seanna Grob, MD, MAS, FACS Clinical Associate Professor of Ophthalmology and Visual Sciences at the University of California, Irvine

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