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GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

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Long-Term Strategies After Stopping GLP-1 Thinking about long-term strategies is crucial for maintaining your results after stopping GLP-1 therapy

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Wegovy is used along with a reduced-calorie diet and increased physical activity for chronic weight management in adults with obesity or with overweight plus a weight-related condition

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Such genetic predispositions could indeed limit the effectiveness of GLP-1 RAs like tirzepatide and semaglutide in patients whose OSA is primarily driven by these underlying physiological mechanisms rather than solely by excess adiposity

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Femminella GD, Frangou E, Love SB, Busza G, Holmes C, Ritchie C, et al

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