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Understanding your specific genetic profile helps predict whether you're likely to need longer-term therapy or if a shorter 12-month course might work for you

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Maintain regular physical activity

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Sensitivity analyses using inverse probability of treatment weighting produced very similar results (eFigure 4 and eFigure 6 in Supplement 2)

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Abstract Tirzepatide (Zepbound), a novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, demonstrates an additive effect, significantly enhancing insulin secretion compared to administering each hormone separately

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Supplementary material The Supplementary Material for this article can be found online at: References 1 BrownleeM

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