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GLP-1 receptor agonists are effective in reducing glucose, enhancing satiety, promoting weight loss, and lowering cardiovascular risks in high-risk patients

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doi: 10.1016/j.coph.2009.09.003

However, there are limitations inherent with this method as a surrogate to evaluating loss of muscle mass (few studies specifically measure muscle mass)

However, this contrasts to findings from earlier infusions of exogenous GIP(1-42), which failed to enhance insulin secretion in individuals with type 2 diabetes (88, 89)

Its a biological response to the removal of medication that was fundamentally altering your appetite signals and metabolism