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In vivo exploration of neuronal-derived extracellular vesicles represents a promising technique to determine the mechanism of action in centrally-acting drugs [89]

While the theoretical long-term benefits to health outcomes are welcomed, the short-term cost impact to health insurers must be considered

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Once-weekly semaglutide 72 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial

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The baseline HbA1c in the tirzepatide arms was 8.23%8.36% and 8.37% in the placebo group