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Semaglutide may safeguard the heart even without significant weight loss.

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Semaglutide reduced major cardiovascular events by 20% compared to placebo

Objective Rheumatoid arthritis (RA) is an inflammatory disease associated with thromboembolic events

In a prespecified analysis of the SELECT trial, semaglutide demonstrated significant reductions in cardiovascular mortality and HF hospitalizations for patients with HF and ASCVD

the proportion of patients who experienced at least one MACE was 3.8% with semaglutide oral tablets and 4.8% with placebo.[1] However, semaglutide oral tablets are not approved for the reduction of CV events