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Four of the trials used double-blind, double-dummy methodology

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Transcriptional control of adipocyte formation

They found that GLP-1 users had a 45% reduced risk of developing dementia compared to those who didnt take these medications
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To reduce the effector functions mediated by the Fc fragment, researchers converted the antibody subtype to a non-glycosylated mouse IgG1 subtype by introducing an N297 to G mutation to achieve deglycosylation
