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Yang Y, Gao L
There have been few trials on the use of antiemetics such as ondansetron and aprepitant in people with severe gastroparesis
Given that PKC and TRPM5 are downstream effectors of Gq signalling in beta cells, our next step involved determining whether the PKC inhibitor (calphostin C) and TRPM5 blocker (TPPO) suppress the triagonist-induced increase in GSIS
The combination did not
Millennials are the most focused on cost, while Gen Z cares more about availability
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