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Abstract Background Establishing whether there is a potential relationship between glucagon-like peptide 1 receptor agonists (GLP-1RAs) and suicidal or self-injurious behaviors (SSIBs) is crucial for public safety

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Notably, the REWIND trial had the lowest proportion of randomized patients who had established cardiovascular disease at baseline (only 31%) of the 6 major trials of GLP-1 receptor agonists

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And thats all before downstream purification begins, which requires its own lengthy steps, including traditional chromatography