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The risk of bias for each included study was assessed using the Cochrane Risk of Bias (ROB2) tool, rating each domain as low [1], moderate [2], or high [3] risk, see Supplement 9

Pregnancy, active suicidal ideation, and certain diabetic complications also warrant avoidance
Keep reading to learn how semaglutide and other GLP-1s improve cardiovascular risk factors

That is a conversation worth having with a provider who knows both options well enough to be honest about the tradeoffs

Mounjaro is more expensive privately, and that difference can determine not only what a patient starts, but what they can realistically continue
