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GLP-RT is commonly used in laboratory research to investigate signaling between three metabolic hormone receptors: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)
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GLP-I(1-37) had no effect on insulin secretion even at concentrations as high as 5 X 10(-7) M
