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In January 2025, the FDA approved an injectable form of semaglutide (Ozempic) specifically for managing chronic kidney disease in type 2 diabetes patients

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You can see from this study the direct correlation between metformin dosing and weight loss over time

The Wegovy pill joins a lower-dose oral semaglutide that was previously approved for the treatment of diabetes

Numerous investigations have explored plausible factors, including hormonal influences (notably, the presence of estrogen receptors in thyroid tissue, and estrogens potential role in stimulating thyroid cell growth and proliferation) and genetic factors, such as the BRAF mutation, as well as other genetic alterations like RET/PTC rearrangements and RAS mutations, which may underlie this gender difference (Leclair et al., 2021)