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These results indicate that GLP-1RAs have direct protective effects against vascular disease through GLP-1R-dependent and GLP-1R-independent pathways

Trial-site personnel and oversight teams remained blinded to group assignments after the 24-week interim analysis until the study was completed and the data was locked

For type 2 diabetes, GLP-1 receptor agonists are typically long-term therapies, similar to blood pressure or cholesterol medications

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10.1016/j.neuropharm.2017.02.013 [DOI] [PubMed] [Google Scholar] 23.Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, et al