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Interestingly, certain bitter compounds, such as denatonium benzoate (DB), have been found to stimulate the secretion of insulin, glucagon, somatostatin, and GLP-1 from pancreatic islets independently of glucose levels

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These medications work by mimicking the action of naturally occurring GLP-1, an incretin hormone produced in the intestines in response to food intake

2023;108(9):e712e719
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Recent advances in the understanding of the pathophysiology of preeclampsia