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associated with severe cognitive impairment requiring external assistance for recovery) hypoglycaemia (baseline to week 57)

specificity: between 97.2% and 100%), these results had a high risk of bias due to design flaws of included studies

Chronic and uncontrolled hypercortisolaemia profoundly affects the physiological functions of key metabolic organs, including the liver, muscles, adipose tissue, and pancreas (17, 24) ( Figure 1 )

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