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=It is speculated that semaglutide (or associated rapid metabolic/vascular changes) may affect optic nerve head perfusion (blood flow) or affect vascular risk in susceptible individuals

However, some people experience nausea or gastrointestinal discomfort with semaglutide, and certain dairy products could exacerbate these symptoms for sensitive individuals

Sublingual or intramuscular B12 bypasses stomach absorption, making these forms ideal during GLP-1 therapy

Patients should not allow appetite suppression to cause chronic under-eating

Treatment goals Patients may have different treatment goals when it comes to weight loss