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Addressing these challenges in pediatric populations requires developing and evaluating cost-effective pathways and strategies to mitigate the economic impact and improve patient outcomes

Ramai D, Mozell D, Facciorusso A, et al

10.2337/db14-1671 80

The question now isnt whether GLP-1s are here to stay

Semaglutide dose-dependently reduced liver enzymes, and resulted in greater NASH resolution (reduced ballooning and lobular inflammation) without worsening of fibrosis, as compared with placebo after 72 weeks of treatment

Lastly as the majority of GLP-1 RAs in this study were semaglutide, this may not apply to all GLP-1 RAs and additionally, because the analysis excluded over 26,000 patients who could not be matched, the results may not apply to the full spectrum of patients taking these drugs in the real world, particularly those with more complex health profiles. MNT spoke with David I