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Metformin use associated with reduced risk of dementia in patients with diabetes: a systematic review and meta-analysis
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doi: 10.1007/s13197-012-0677-0
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Nausea, constipation , and fatigue are the most commonly reported issues
Newer systematic reviews and meta-analyses suggest a slight increase in pancreatitis overall, although this may not be significant once background medications are considered, and no clear increase in pancreatic cancer has been consistently shown
