obesity drug glp-1 news today New oral delivers up to 12% weight loss in 36 weeks Market Overview: GLP-1 Agonists and
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Key Takeaways Retatrutide activates GLP-1R, GIPR, and GCGR simultaneously, making it structurally distinct from both semaglutide (GLP-1 only) and tirzepatide (GLP-1 and GIP only)

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FDA Crackdown on Compounded GLP-1s (Regulatory): On February 6, 2026, the FDA announced a formal intent to restrict the use of active pharmaceutical ingredients (APIs) for non-approved compounded GLP-1 drugs, targeting "mass-marketed" alternatives from companies like Hims & Hers as the national supply of brand-name versions stabilized
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*Correspondence: Guobing Chen, [email protected]