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Research from the STEP trials, which studied semaglutide 2.4mg weekly, found that approximately 75% of the weight lost was fat mass rather than lean mass
So, if you have a 10 mg/mL concentration, then 0.5 mL would contain 5 mg of the drug

Identification of chronic stress-activated regions reveals a potential recruited circuit in rat brain
But now to extend this to people who are not such high risk, but these large trials, we keep learning more
Biochem Soc Trans (2013) 41(1):1729
