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Black adults report the highest usage of GLP-1 medications among racial and ethnic groups, at 18%, followed by Hispanic adults at 13%

Nevertheless, the mechanistic parallels with approved GLP-1 medicines combined with the substantial dietary restriction retatrutide may induce make nutritional vigilance a reasonable and prudent clinical consideration

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This study not only found that the cGAS-STING-ferroptosis pathway was a druggable target in joints, but also pioneered a new flexible delivery platform that resolved the key limitation of low local drug concentrations in joints after systemic administration, and offered a cartilage-protecting perspective for RA

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