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Transl Med Commun

Furthermore, the administration of GEP44 results in profound reductions in food intake and body weight in DIO rats
At the same time, sustained receptor engagement may induce adaptive responses such as receptor desensitization, endocrine feedback suppression, or compensatory pathway activation

Brennan IM, Feltrin KL, Horowitz M, Smout AJ, Meyer JH, Wishart J et al
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