glp-1 drugs food industry impact news today What retailers should know about consumers taking GLP-1s for weight loss GLP-1s' direct and indirect impacts

Diabetes Obes Metab (2018) 20(2):46873

The action on kidneys appears to be directly through the effects also on renin-secreting cells of the juxta-glomerular apparatus, whose stimulation may lead to increased natriuresis and reduce hyperfiltration, and indirectly by the reduction of angiotensin II levels, the increase in nitric oxide with consequently endothelial vasodilation and the improvement of risk factors of kidney disease (hyperglycemia, hypertension, obesity) ( Figure 2 )

As the powerhouse of the cell, our mitochondria generate the critical energy needed for our cells (including our muscle and skin cells) to function correctly

In addition to having effects on how your body metabolizes glucose and processes certain hormones, GLP-1 receptor agonists, as well as dual agonists like tirzepatide, act on receptors in your brain to curb cravings

Aviles-Olmos I & Kefalopoulou Z (2012) Aviles-Olmos I, Kefalopoulou Z, Djamshidian A, Limousin P, Dickson J, Lees A, et al

DPP-4 Inhibitors DPP-4 inhibitors (sitagliptin, saxagliptin, linagliptin) work on the same incretin axis as GLP-1 RAs