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Oxidation and hydrolysis can affect the lipid moiety as well as the peptide backbone, generating degradation products that are specific to tirzepatide and would not be encountered with standard peptides

If one medication is not producing adequate results, switching to another is preferable to stacking them

This is much higher than the 2.1 rate for bupropion-naltrexone users and 1.1 for sleeve gastrectomy patients [4]

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