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The case report of a post-thyroidectomy patient requiring a 25% levothyroxine dose reduction on semaglutide illustrates how significant the interaction can be in this population

As anticipated, among those patients who remained on treatment with semaglutide by the EOS, 78.2% and 78.9% of those in the low/no CKD risk cohort and CKD cohort, respectively, were being administered the full dose of 1 mg weekly at that time whereas only one patient remained with the initial dose of 0.25 mg weekly

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[205] recently published the study protocol of a phase 2, double-blind, randomized, placebo-controlled trial termed RESET1 (REducing cardiometabolic risk with SEmaglutide in Type 1 diabetes)