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More serious but less common risks include pancreatitis, gallbladder disease, acute kidney injury (particularly in the setting of dehydration from gastrointestinal symptoms), and hypoglycemia when used in combination with insulin or insulin secretagogues

A pooled analysis of CVOTs showing that therapy with GLP-1 RA does not increase the risk of acute pancreatitis or pancreatic cancer

One study extracted data from the US Food and Drug Administration (FDA) on inadvertent exposure in women participating in clinical trials of GLP-1 Ras (Parker et al

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Clinical Pharmacology Review: NDA 215866

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