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Other medical reasons for pausing treatment include severe gastrointestinal adverse effects that don't improve with dose reduction or supportive measures, acute kidney injury related to dehydration from gastrointestinal side effects, severe hypoglycemia (particularly when combined with insulin or sulfonylureas), and worsening diabetic retinopathy
JAMA Netw Open 2025;8:e2457349.ArticlePubMedPMC 116

These findings are consistent with data accessed July 17, 2024

It belongs to a new group of medications called triple-agonist metabolic drugs because it activates three hormone receptors that help control appetite and metabolism
Retrieved August 1, 2025, from 4

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