average weekly weight loss semaglutide 2.4 mg vs 1 mg and placebo in #obesity with T2 #diabetes Better loss, better reduction in waist circumference and slightly better HbA1c lowering (sugars) with fewer other sugar-lowering In clinical trials, after 12

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Each has different indication, dose, and reimbursement status: The most important distinction for foreign patients: Ozempic and Wegovy are the SAME active molecule (semaglutide) at DIFFERENT approved doses for DIFFERENT indications

New insulin glargine 300 units/mL versus glargine 100 units/mL in people with type 2 diabetes using oral agents and basal insulin: glucose control and hypoglycemia in a 6-month randomized controlled trial (EDITION 2)

These domain-level judgements provide the basis for an overall risk-of-bias judgement for the specific trial result being assessed

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So, lets explore why GLP-1 medications cause constipation and how to manage this really uncomfortable side effect