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Why the FDA is concerned about unapproved GLP-1 pills (including tirzepatide) The FDA has issued detailed warnings about unapproved GLP-1 drugs marketed for weight loss, including products claiming to contain tirzepatide (official FDA safety alert)

Waist circumference, an established marker of central adiposity and cardiometabolic risk, decreased significantly from baseline to week 36 in all treatment groups

Many patients choose telehealth consultations because they provide convenient access to physician-guided weight-loss care from home

The GIP (glucose-dependent insulinotropic polypeptide) receptor was historically underestimated because GIP infusion in people with T2D shows minimal insulinotropic effectsuggesting T2D causes GIP receptor downregulation

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