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When people stop taking the new generation of weight-loss drugs, they pile back on the kilos four times faster than they would after ending diet and exercise regimes, new research found Thursday.

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While challenges with adherence, side effects, and weight regain upon discontinuation have prompted the search for additional strategies, targets like GLP-1R, GIPR, and GDF8 (Myostatin) still remain the most highly relevant and active areas of research for developing effective obesity treatments

Postprandial reduction in hunger was greater after RYGB than OAGB from baseline to 12 months

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