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(2023) reported that semaglutide reduced both baseline and relapse-like alcohol consumption in rats, blunted ethanol-induced hyperlocomotion and NAc dopamine release, and increased expression of dopamine-metabolizing enzymes

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In vitro studies, HepG2 cells treated with palmitic acid (PA) were found that dulaglutide significantly reduced liver lipid accumulation and gene expression related to lipid drop-binding proteins, de novo adipogenesis and TG synthesis