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In its phase 3 TRIUMPH-4 study, the company reported that its new triple-agonist injection, retatrutide, produced an average 28.7% reduction in body weight over 68 weeksa result that surpasses even the blockbuster Zepbound

Use was also associated with reduced risks of adverse clinical outcomes in people with pre-existing SUDs

however, GLP-1 receptor agonists were associated with a higher risk of discontinuation of endoscopy, possibly owing to a higher risk of retained gastric content

These celebs are getting real about the pros and cons of weight-loss medications.

It comes as a pre-filled pen injector with a dosage of 1 mg/0.5 mL

Thus, GLP-1 RAs may provide a new option for pharmacological treatment of obesity.